Making a Difference

St. Luke's College has been providing healthcare education for over 120 years. We are the region's leader in hospital-based education where students receive the extraordinary opportunity to make a difference in the lives of others.  

Our Mission

As an institution of higher education, St. Luke's College provides high quality, health system-based education to individuals who desire to become competent and compassionate health care providers.

Our Vision

A recognized innovative leader exclusively educating healthcare professionals.


FOCUS Values are the fundamental beliefs and operating principles of the UnityPoint Health System of Hospitals and Colleges. The FOCUS values include:

  • Foster Unity
  • Own the Moment
  • Champion Excellence
  • Seize Opportunities

Real Life Experiences

St. Luke's College is located on the campus of UnityPoint Health-St. Luke's in Sioux City, Iowa.  Students receive a hospital-based education that combines classroom learning with clinical practice where students can:


  • Explore their field of study with real-life experiences.
  • Utilize advanced techniques and leading technology at UnityPoint Health - St. Luke's, as well as in rural community hospitals, clinics, schools, and home health agencies.
  • Get to know their classmates and faculty with small class sizes.

Graduates in Demand

The health care industry projects higher than average growth through the year 2032, with nearly 1.8 million openings projected each year.  Employment of registered nurses and radiologic technologists are project to grow 6%, and employment of respiratory therapists are projected to grow by 13% making an education in healthcare a great career choice.